Back in the late 90s and early 2000s, there was a criminally underrated sitcom called "Becker" starring Ted Danson as a grumpy, curmudgeonly, cheapskate GP working out of a run-down office in the Bronx. It focused on the many comic travails of his life, and his interactions with a blind black newsstand owner, a very attractive coffee shop owner (played by the inimitable Terry Farrell, who looked amazing back then and still looks pretty damn good today), and various others. Including Shawnee Smith, who starred in the "Saw" film series but never quite got to be as great as she was in this show.
(Farrell was replaced halfway through Season 4 by the almost-equally-hilarious Nancy Travis. She was good, but not quite as good.)
It was and remains one of the funniest shows ever to air on TV. And every grumpy introvert, ever, can relate to it. This was Gregory House, M.D., years before "House" was ever aired- less drama, less implausible medical conundrums, and less focus on human relationships, but much, much funnier in every way.
Here are a few of my favourite episodes- you can find most of them on YouTube now for free, thankfully: